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In most industrialized countries, clinical B12 deficiency is relatively rare, with many of the causes being of ileal or gastric origin (Green & Miller, 2022)

They also noted that cells cultured with IGF-1 exhibited better morphology due to the increased number of gap junctions between theca-granulosa cells and granulosa cell-oocyte (61)

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The synaptic changes Dihexa induces take days to fully develop and persist weeks after the initiating stimulus

doi:10.3389/fmolb.2019.00116 [54] Wessling-Resnick M

("NH" = non-Hispanic)