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Newly differentiated OLs extend their processes and quickly rearrange their membranes to generate internodes around multiple axons through a series of coordinated steps that include: (1) identification and signaling with the target axons, (2) axonal wrapping with membrane outgrowth, (3) transporting membrane components, (4) compacting myelin sheaths, and (5) node establishment (Simons et al., 2024)

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The purified garlic fraction also inhibited renal Na + /K + -ATPase, likely by inhibiting the Na + -pump at the tubular Na + -reabsorption level in the kidneys (210)

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This dysregulation disrupts oxidative stress balance, impairs insulin signaling pathways, and alters both lipid and glucose metabolism[179]

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