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Suganuma, et al

doi: 10.1007/s10534-005-3688-8 137 VardatsikosGPandeyNRSrivastavaAK

Tschp MH, Speakman JR, Arch JRS, Auwerx J, Brning JC, Chan L, et al

PMCID: PMC6472203

However, in the context of chronic COPD, the function of M2 macrophages may be impaired, leading to an imbalance with M1 macrophages ( Modulating macrophage polarization, inhibiting pro-inflammatory signaling pathways, and promoting tissue repair mechanisms are potential approaches for attenuating inflammation, reducing tissue damage, and improving lung function in individuals with COPD