Use with caution in men with obstructive sleep apnoea, thrombophilia, epilepsy, or pre-existing polycythaemia
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Handling Precautions for Healthcare Providers Healthcare professionals must ensure they take the required precautions when administering methylcobalamin injections to uphold cleanliness and prevent contamination risks
Drug Interactions Several common medications reduce B12 absorption: Metformin (diabetes) significant reduction in B12 absorption Proton pump inhibitors (Omeprazole, Pantoprazole) reduce stomach acid needed for absorption H2 blockers (Ranitidine, Famotidine) similar effect to PPIs Colchicine (gout) may reduce B12 absorption If you take any of these medications long-term, B12 supplementation is strongly recommended
Choon Kiat Ong, [email protected] These authors have contributed equally to this work and share last authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers