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Because the model was developed to investigate the effect of the HGF pathway on HCC cells, the literature was mined rigorously to be able to calibrate the model by only using datasets from hepatocytes 33 or HCC cell lines

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In vitro studies using endothelial cell models have demonstrated effects on fibroblast migration rates, endothelial cell tube formation in angiogenesis assays, and cytoprotective mechanisms in cell culture models exposed to oxidative and chemical stressors

It was reported that ADSCs protected cells from oxidative stress by enhancing the activity of antioxidant enzymes (e.g., superoxide dismutase and glutathione peroxidase) and producing various antioxidant proteins [51]