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All mice were maintained on a 12 h light/dark cycle at 22C, with unrestricted access to standard rodent chow and water, and were housed under pathogen-free conditions

Evaluation of butylated hydroxyanisole, myo-inositol, curcumin, esculetin, resveratrol and lycopene as inhibitors of benzo[a]pyrene plus 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in A/J mice

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[1] The antibiotics metronidazole, vancomycin, or fidaxomicin, will cure the infection

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This proteolytic cleavage induces conformational changes that favors S-protein recognition by host cell membrane proteases (i.e., TMPRSS2, CTSL)