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After reconstitution: Store at 28 C , protect from light, use aliquots to reduce handling, and avoid repeated temperature cycling

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Handb Clin Neurol 129:325 Polski B, Sosnowska-Sienkiewicz P, Szydowski J, Januszkiewicz-Lewandowska D (2023) Applications of the grading scales for the detection of ototoxicity in children after treatment of neuroblastoma and extracranial germinal tumor

The exact timing varies based on individual factors including blood flow to the injection site, subcutaneous tissue thickness, and metabolic rate

Article PubMed PubMed Central Google Scholar Satija, A

In addition, endothelial dysfunction and initiation of atherogenesis are known to trigger by activating the nuclear factor-B (NF-B) signaling pathway and NLRP3 (NOD-like receptor protein 3 or NLR family pyrin domain containing 3) inflammasome pathway in endothelial cells both in vitro and in vivo (Seldin et al., 2016