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Clonal evolution under therapy intersects with adaptive non-genetic mechanisms, providing a transition to adaptive resistance mechanisms discussed below

In this review, we will focus on the metabolic effects of IGF-1, the concept of metabolic syndrome and its clinical manifestations (impaired lipid profile, insulin resistance, increased glucose levels, obesity, and cardiovascular disease), discussing whether IGF-1 replacement therapy could be a beneficial strategy for these patients

doi:10.6118/jmm.2017.23.2.79

In fatty acid metabolism, long chain fatty acids in the cytosol cannot cross the mitochondrial membrane because they are negatively charged

Antioxidative and neuroprotective effects of curcumin in an Alzheimers disease rat model co-treated with intracerebroventricular streptozotocin and subcutaneous d-galactose

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