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Availability: InStock
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doi: 10.1016/j.bcp.2020.113829

The company started a phase 2 trial studying VK2735 in obese patients back in September 2023 with the purpose of assessing the safety and efficacy of the once weekly subcutaneous drug

For 78c, the most important interaction in the active site appears to be a hydrophobic interaction of C4 group and Trp176 and the hydrogen bond between the 2-ketoresidue and the side chain amide of Asp183 [78]