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338 Similar decreases in astrocytic expression of glutamate transports are characteristic for animal models of epilepsy, 339,340 and genetic ablation of EAAT1/2 triggers seizures

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These reports are anecdotal there is no published case series or trial safety database for injected GHK-Cu, so their frequency and severity are genuinely unknown

These effects, induced by arecaidine, appear to be mediated by ROS production as the co-incubation with the antioxidant N -acetyl-l-cysteine decreases ROS levels and the apoptotic index in U87MG and U251MG GBM cell lines