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Assessing GSH status is critical for studying oxidative stress mechanisms and downstream effects of oxidative damage

Medinfo 8 Pt 1:771-5, 1995

R., & Liu, D

Cholesterol can induce PD-1 expression, impede CD8 + T cell proliferation, and diminish levels of toxic cytokines (such as TNF-, IFN-) by amplifying endoplasmic reticulum stress, thereby fostering immune evasion by tumor cells and functional impairment of CD8 + T cells