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The molecular formula and weight for nucleic acid (Supplementary Table 1) was estimated using the GC (guanine-cytosine) content of Synechococcus elongatus (60.67%) 89 for DNA and Escherichia coli for RNA (50.8%) 90

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Such discrepancies point out to possible missing links in the metabolic pathways based on the current status of the gene sequencing and annotations

While thresholds exist to characterize ruminal acidosis, the specific pH value at which damage occurs to the ruminal epithelium, microbial community structure and activity are altered, and feed intake is depressed likely varies among individual animals