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These include small molecule inhibitors that block the kinase activity of c-Met, monoclonal antibodies that neutralize HGF or inhibit its binding to c-Met, and multi-targeted inhibitors that disrupt both the HGF/c-Met and other RTK pathways

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Grammer TB, Kleber ME, Silbernagel G, Pilz S, Scharnagl H, Lerchbaum E, Tomaschitz A, Koenig W, Mrz W