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ChIP assays were performed using Kasumi-1 and K562 cells, as well as HEK293T cells transduced with GFP-ASXL1 1-645 -WT, GFP-ASXL1 1-645 -I574D, GFP-ASXL1 1-591 -WT or GFP-ASXL1 1-591 -I574D (5 10 cells per condition), following protocols 39

Findings indicated that the risk of developing AA was significantly higher in individuals under 45 years of age, with a hazard ratio of 1.651

It is important to note that, compared to astrocytes, the regulation of the multifunctional transmembrane receptor LRP1 on the surface of neurons has the opposite effect on glucose uptake capacity [124]

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Antioxidant therapies involving natural products, nanomaterials, hydrogels, microneedles, and antioxidant enzymes help alleviate these effects and improve the condition of AD

Also, SelenoP concentrations and GPx activity were not reduced in serum from individuals with CD compared to healthy volunteers (Fig