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PMID: 7511050

Chronic heat stress and prenatal development in sheep: I

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Interestingly, in sheep, endotoxin-induced lung maturational effects occurred without concomitant increases in fetal cortisol levels, suggesting alternative cortisol-independent mechanisms yet to be identified (307)

Similarly, in laryngeal cancer, GPx1 upregulation was associated with lymph node metastasis and cancer stage and was an independent predictor of patient survival (HR, 2.101, 95%CI, 1.0114.367) [137]

The hypoxic TME induces the HIF-1-mediated upregulation of PD-L1, leading to CD8 + T-cell dysfunction 261