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Another study introduced an MMP-clearable sequence at both ends of a bioactive peptide while additionally incorporating thiol-functionalized crosslinkers at each end, thus developing C-IPESLRAG-bioactive peptide-IPESLRAG-C-G to enable conjugation with norbornene-functionalized PEG [344]

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Evidence remains largely preclinical, but findings indicate possible benefits in reducing inflammation and aiding recovery in digestive tissues, especially in conditions involving ulcers or irritation

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