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Pickart's own publications and conceptual frameworks have shaped much of the discourse around the compound, and the research community working specifically on GHK-Cu has had substantial overlap with Pickart's collaborations

In human fibroblasts incubated for 10 min with 500 microM of [14C] cyanide, the accumulation ratio was 25 at 37 degrees C (10.45 +/- 1.51 mM) and 11.9 at 4 degrees C

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It binds IGFBP-1, IGFBP-2, IGFBP-4, IGFBP-5, and IGFBP-6 with somewhat lower but still substantial affinity