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Some animal studies also examine neuroendocrine responses associated with melanocortin receptor activation

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Isolation of a new gene GS2 (DXS1283E) from a CpG island between STS and KAL1 on xp22.3

Similarly, a review with five RCTs (449 participants) also found that 84% of individuals receiving acupuncture experienced a reduction in symptom severity, in contrast to 63% of those undergoing pharmacological treatment, indicating that acupuncture was significantly more efficacious than either pharmacological therapy or no targeted intervention [121]