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In individuals with overweight or obesity, treatment with semaglutide was associated with significant reductions in bodyweight, with a mean placebo-subtracted weight loss of 12.4% relative to placebo after 68 weeks reported in the STEP 1 trial

Elevated B12 may occasionally be associated with certain cancers, particularly haematological malignancies and liver cancers, but it does not directly indicate cancer is present

1 2 "Living With Pernicious Anemia"