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Because the RI effect on memory and Rac1 activity was only evident 22 h (but not 8 h) after the initial training, there may exist a time window in which the Rac1 activity level is sensitive to endogenous modulation (Liu et al., 2016)

Even if the peptide does not directly bind to Cu, covering His residues (such as His259 and His263) will destroy the stable coordination of Cu and reduce its catalytic efficiency (Joompang et al., 2020)

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pneumoniae infection induces H3K4me2 enrichment in respiratory epithelial cells ( in vitro : in -glucantrained monocytes, promoters and enhancers of inflammation- and immunity-related genes gain H3K4me1, H3K4me3, and H3K27ac marks, maintaining transcriptionally active chromatin and enabling enhanced cytokine production upon restimulation (153)