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Regarding molecular mechanism of ROS against biomolecules, free species like NO , NO 2 , H 2 O 2 , and ONOO - can cross lipid membranes and carry signals across organelles, while other types of ROS have limited half-life or physical properties that contribute to damaging of other biological molecules

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Overview of the Science Research suggests that L-carnosine's protective effects extend beyond telomere preservation to include advanced glycation end product (AGE) inhibition and protein carbonylation prevention [1][2]

28 reported that sumatriptan (0.3 mg/kg/day, intraperitoneally for three days) exerted nephroprotective effects in cisplatin-treated mice by decreasing serum creatinine, BUN, and MDA levels, while enhancing renal antioxidant defenses (SOD, GPx)

USA 94 , 78857890 (1997)