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N Engl J Med (1986) 315:4857

Lrig1-expression confers suppressive function to CD4 + cells and is essential for averting autoimmunity via the Smad2/3/Foxp3 axis

Please consult your doctor if these side effects persist for a longer duration

Boese AC, Le QE, Pham D, Hamblin MH, Lee JP

Nat Rev Neurol (2015) 11(12):71124

In the same study, they also showed that after chronic Mn injection (daily for 30 days) in mice, there was a reduction in TH-positive cells in the substantia nigra