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Major mechanisms include: decreased membrane transport of the drug, increased cytoplasmic detoxification, increased DNA repair, and increased tolerance to DNA damage

By elevating NAD+ levels and optimizing energy metabolism, it achieves favorable effects in body weight control and blood glucose regulation

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However, the fast reaction rates of Prxs with H 2 O 2 together with their high intracellular abundance put redox-regulated proteins at a clear disadvantage with respect to direct reactions with H 2 O 2 [102,103]

There is still no safety data on what a decade of use looks like

We detected in isolates from both sources an IncP-6 plasmid harboring a bla KPC-2 gene (p121SC21) similar to the one described by Dai et al