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[DOI] [PubMed] [Google Scholar] 35.Martin JL, McMillan FM

Commercial proteomics solutions such as SomaScan and Olink have significantly contributed to the field of biomarker discovery (74, 75)

Moreover, pharmacological inhibition of this cleavage delays neurodegeneration [386, 387]

Early symptoms are often subtle, with occasional hypertension, mild oedema, and increased nocturia (9, 10)

Eukaryotic translation initiation factor 3 subunit f (eIF3f) counteracts this process through deubiquitination, rescuing PHGDH from proteasomal degradation by removing K48-linked ubiquitin chains