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There is a +/- 5% incidence of cancer in "single nodules" in adults, but up to 18% of those found in children are malignant

Nat Rev Mol Cell Biol 22(2):7595

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Dry eye is one of the most common corneal diseases, which can result in ocular pain and even visual damage

Liao, Y., Wang, Y., Lin, Y., Xiao, Y., Mohan, M., Jaman, R., Dong, H., Zhu, J., Li, X., Zhang, C., Chen, G., & Zhou, J