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(2021) employed tandem mass tag proteomics (TMT) and mass spectrometry (MS) to analyze PBMC, identifying differential expression of proteins regulated by the liver X receptor-retinoid X receptor (LXR/RXR) pathway, which modulates lipid metabolism and inflammation, potentially influencing the expression of pro-inflammatory cytokine genes (Schulman, 2017)

Qi F, Zhang F

Consistent with this hypothesis, interrogation of our gene expression microarray data sets revealed increased expression of several JNK regulatory genes including the toxicity and JNK inducer TAJ ( TNFRSF19 , 8.33-fold, adjusted P -value 1.25 10 18 , Supplementary Table 1), and JNK target genes including the p53-inducible proteins TP53I3 ( PIG3 , 5.02-fold, adjusted P -value 1.73 10 16 ) and CDKN1A ( p21 , 4.87-fold, adjusted P -value 9.62 10 15 ) in GSTP1 knockdown cells

Preliminary data for NACs effectiveness in several psychiatric diseases was presented in this review, indicating that NAC might be beneficial in similar human conditions

In addition to markers of protein oxidative damage, 8-oxo-dG, a marker of DNA oxidative damage, was significantly elevated in both cerebellum and BA22 from the autism cases relative to controls

The crystal structure of meningococcal FetA indicates that this outer membrane protein binds to and perhaps directly internalizes ferric iron, consistent with its broad specificity (Saleem et al., 2012