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Data availability The mass spectrometry proteomics data are provided as Supplementary Data 1 and have been deposited to the ProteomeXchange Consortium ( via the PRIDE partner repository with the dataset identifier PXD062777

In general, consistent with preclinical studies, RSV supplementation (500 mg/day, P.O for 4 weeks) raised erythrocyte PPAR- and Sirt1 expression and serum TAC and attenuated the total/HDL cholesterol ratio in CHD patients with type 2 diabetes [198]

Notably, after a 4-week washout period these beneficial effects diminished, with the exception of clinical severity scores

However, whether ferroptosis plays a role in ALOX-12mediated NASH remains an open question

Arch Gynecol Obstet