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However, despite the advantages of lipid-based nanodrug carriers, they still face challenges related to solubility, stability, and aggregation ( Polymer-based nanodrug carriers are another widely used carrier system, typically made from synthetic or natural polymer materials such as polylactic acid (PLA), polyethylene glycol (PEG), and poly (D,L-lactic-co-glycolic acid) (PLGA) (Ibrahim et al., 2022

Nociceptors are interleukin-1beta sensors

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Proteintech, Rosemont, IL, USA) were used for western blotting

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10.3390/ijms24065486 51 SuburuJ.ChenY