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Funding This work was funded by the Yunnan University Undergraduate Innovation Fund, S202410673138, Yunnan University Medical Research Foundation Department of Radiology, YDYXJJ20250024, Yunnan University Graduate Research Innovation Fund, KC-252512222

Table 3 Actionable research priorities and proposed interventions for advancing Parkinsons disease treatment

Astrocytic autophagy plasticityboosting degradation of pathological proteins Neurons exposed to -amyloid oligomers fail to cope with this proteotoxic stress, leading to a reduction in the expression of autophagy-related genes (MAP1LC3B/LC3B and SQSTM1/p62, two key autophagy-related genes) alongside a decrease in microtubule-associated protein 2 (MAP2)

Theres analysis supporting that proline can be considered as a biomarker assisting diagnosis and prognosis [163]

This reagent reacts with the thiol groups of GSH which convert 2-nitro-5-thiobenzoate (NTB ) to NTB 2 , thereby producing a yellow color, which can subsequently be quantified ( Glutathione Peroxidase GPx is measured by adding glutathione reductase (GR) to the sample after which nicotinamide adenine dinucleotide phosphate (NADPH) is transformed to a reduced state, allowing a decrease in absorbance to be subsequently measured (32)

10.1155/2021/6634309 107 FernandesR