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The diagnosis of this disease is made by observing increased chromosomal breakage, rearrangements, or exchanges in cells after exposure to carcinogens such as diepoxybutane

Additionally, Western blotting data showed that the active forms of caspase-1 (cleaved casp-1) and GSDMD (GSDMD-NT) in pancreatic tissue were restored in STC-injected mice pretreated with high-dose LC (Figures 6EG)