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The MHRA product information for hydroxocobalamin preparations lists several recognised side effects that patients should be aware of before commencing treatment

References Ferrer-Lorente R, Cabot C, Fernndez-Lpez JA, Alemany M

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that no important aspects of the study have been omitted

For patients with a history of treated and stable malignancies, initiate EGRIFTA WR therapy only after careful evaluation of the potential benefit of treatment relative to the risk of re-activation of the underlying malignancy