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The therapeutic era of peptides began in 1921 with the discovery of insulin, a breakthrough that revolutionized diabetes and helped establish biologic therapies in medicine Since then, peptide hormones like oxytocin and human growth hormone (GH) have entered clinical use, and glucagon-like peptide-1 (GLP-1) receptor agonists such as semaglutide are now widely prescribed for obesity and metabolic diseaseconditions increasingly recognized for their effect on orthopaedic outcomes

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Instead, the research reinforces a simpler message: symptoms such as persistent fatigue, numbness, memory problems or balance difficulties deserve proper medical evaluation because vitamin B12 deficiency is one of several potentially reversible causes

Weng, Y.-S

Peptide-mediated biomimetic regrowth of human enamel in situ

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