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3 Molecular functions of ChaC1 ChaC1 and its homologues function as -glutamyl cyclotransferases (GCTs) that specifically degrade glutathione

Varying intervals of maintenance doses will then follow it

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The importance of the tumour microenvironment in the progression and treatment response of CRC is well documented, with high infiltration of T-cells associated with improved prognosis (74), suggesting that in addition to tumour cell-specific effects, metformin-mediated modulation of host immunity may also underlie its radiosensitising effects

agrees to be personally accountable for the authors own contributions and for ensuring that questions related to the accuracy or integrity of any part of the work, even ones in which the author was not personally involved, are appropriately investigated, resolved, and documented in the literature