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Abraham S, Soundararajan CC, Vivekanandhan S, Behari M

This duality underscores the importance of context-specific modulation and highlights the current lack of reliable biomarkers to guide patient selection for autophagy-targeting combinations

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Consequently, pyridoxine significantly influences the adrenergic, serotonergic, and glutamatergic systems ( Pyridoxine may also exert a protective effect on the nervous system by regulating the glutamatergic system and thus modulating GABA and glutamate levels (60)

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The GSH- targeted liposomes showed a higher and specific accumulation in the perfused hamster brain, and less in a selection of other tissues analyzed (including heart, lung, liver, spleen and kidney), when compared to the control liposomes which were not (or hardly) detectable in brain, but to a relatively higher extend in lung, kidney and liver tissues 3 days after the last injection