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Most patients experience no adverse effects, and when present, theyre typically mild and transient including temporary digestive changes as the gut adjusts, minor nausea (usually resolving within days), or altered bowel patterns during initial therapy

LDN: The most common side effects are transient and often dose-dependent

The most commonly used solution is a hypertonic dextrose solution (15-25%) mixed with local anesthetic like lidocaine

The outcome measures were the Visual Analog Scale (VAS), Japanese Orthopaedic Association (JOA) score, Oswestry Disability Index (ODI), serum inflammatory factor expression, adverse surgical events, duration of postoperative hospitalization, and modified MacNab criteria

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Evaluation of intracellular magnesium and calcium concentration in patients with migraine