nadph-dependent glutathione reductase mechanism NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications NADPH: Reductive Biosynthesis and Cellular

Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds to reduced glutathione (l-g-glutamyl-l-cysteinyl-glycine) and participating in antioxidant defense through a number of mechanisms, including the repair of ROS-induced damage and the detoxification of xenobiotics present in air pollutants 50

It has been reported that autophagy contributes to resistance development in response to PTX treatment [103]

It isn't anymore.

K., Shukla, S., Shukla, V., & Singh, S

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Interrogation of the perturbed gut microbiota in gouty arthritis patients through in silico metabolic modeling