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Three key challenges persist: lack of core markers for highly efficient immune regulatory donors (specific bacterial genus combinations, metabolite profiles) leading to unstable transplantation effects

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Structure of human drug transporters OATP1B1 and OATP1B3

Consequently, single-modality biomarkers frequently fail to generalize because they are sensitive to context (cycle phase, progesterone exposure timing, stimulation protocols, and tissue/cell-type composition), so an apparent signal in one layer may reflect unmeasured confounding rather than functional competence [447]

Often dubbed the "master antioxidant," it plays a crucial role in numerous bodily functions, including detoxification, immune system support, and cellular repair

As reported by Lin et al., the combination of resveratrol and temozolomide affects malignant glioma by inhibiting ROS/ERK-mediated autophagy [187]