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90 subjects received treatment, with 36 receiving a high dose of Phase 2 (1000 mg, WKBE HIGH), 18 receiving a low dose (700 mg, WKBE LOW), and 36 receiving a matching placebo (microcrystalline cellulose, PLA) three times a day for 12 weeks

Paris 91 (3-5), 173178

Sies, H., Redox Biol ., 2017, no

of Minnesota) for providing the strains used in this study

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Then, we enhanced the expression of the N-terminal (amino acids 1212), middle fragment (amino acids 213424) and C-terminal (amino acids 425637) of Myc-GCLC and full-length CENPT in 293 T cells