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The AML-1/ETO fusion protein is a dominant negative inhibitor of transcriptional repression by PLZF

Exercise also can elevate apoptosis levels, especially in scenarios such as mammary tumorigenesis in rats [74]

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Dasatinib + quercetin, the most studied senolytic combination, works through different anti-apoptotic pathways (SCAPs) and does not specifically target the FOXO4-p53 axis