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Hwa V, Haeusler G, Pratt KL, Little BM, Frisch H, Koller D, Rosenfeld RG: Total absence of functional acid labile subunit, resulting in severe insulin-like growth factor deficiency and moderate growth failure

Nucleus-translocated ACSS2 promotes gene transcription for lysosomal biogenesis and autophagy

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Skin Benefits: Accelerates wound healing and scar fading Reduces acne-related inflammation and redness Enhances skin elasticity and hydration Supports angiogenesis (formation of new blood vessels) Hair Benefits: Repairs damaged scalp tissue May reactivate dormant hair follicles Reduces inflammation-related hair loss (e.g., telogen effluvium) 2

doi: 10.1098/rstb.2010.0149 8

Conversely, CKD may also induce oxidative damage in other pathological conditions [308, 318, 319]