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Despite that mitochondria are exposed to the generation of oxidant species, the existence of an efficient antioxidant defense system, of which mGSH is a critical component, prevents or repairs oxidative damage generated during normal aerobic metabolism (Mari et al., 2013)

Generally, glutamine can be converted in the mitochondria to supplement the tricarboxylic acid (TCA) cycle, or it can be completely oxidized to produce ATP

Metabolite signature associated with stress susceptibility in socially defeated mice

R -ALA was synthesized through the resolution of racemic ALA by enzymatic esterification of the carboxylic group, which consists of four carbon atoms away from the stereogenic center (Scheme 21)

By preventing this damage, glutathione preserves cellular NAD+ pools

Activation of a novel human transforming gene, ret, by DNA rearrangement