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Insulin resistance is linked to several negative consequences, such as endothelial dysfunction, reduced cardiac diastolic relaxation, impaired vascular relaxation, decreased coronary blood flow, and increased susceptibility to ischemia

Glutathione has the effect of preventing pigment accumulation and is used in vegetables and fruits to effectively prevent browning

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A recent case report of a young woman born with generalized congenital dermal melanocytosis who subsequently developed bilateral nevus of Ota and eruptive blue nevi highlights this association [69]