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*Correspondence: Predrag Sikiric, [email protected] This article was submitted to Gastrointestinal and Hepatic Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Cardiovasc Res 2017;113:411421

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They represent what rigorous clinical development looks like: Phase I through Phase III trials, post-marketing surveillance, and manufacturer accountability