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A clinical study investigated the efficacy of an Astragalus -containing formula (Huangqi Xuming Decoction) in treating Alzheimers disease (AD) patients with spleen-kidney deficiency syndrome

In addition, the microbial activity induced by indigestible amino acids promotes the production of metabolic end products including short-chain fatty acids (SCFA

Additionally, Protein kinase C (PKC) pathway activation can induce insulin receptor substrate 1 (IRS-1) phosphorylation, inhibiting insulin signaling through downstream effectors such as Akt, phosphoinositide 3-kinase (PI3K), and glucose transporter 4 (GLUT-4) (Ritter et al., 2015