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Huang et al., 2025), with approximately 83% of children experiencing at least one episode by the age of three (Teele et al., 1989

The outer membrane protein MARCH5 controls quality control and mitochondrial dynamics [141, 142]

In experimental BP in adult mice, both C5-deficient and C5aR1-deficient mice developed significantly less skin lesions compared with wild type animals [72, 110]

Preliminary research suggests that these mechanisms may be similar to those observed with exogenous hGH therapy, including the activation of the adrenergic receptors and increased lipolysis in adipocytes [5]

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For example, rosmarinic acid from Rosmarinus officinalis (rosemary) and carnosic acid from Salvia officinalis (sage) have been shown to activate Nrf2 and upregulate downstream antioxidant genes (Hu et al., 2023