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Figure 8: Kaplan-Meier Curves for Overall Survival in PARAMOUNT Treatment of Recurrent Disease After Prior Chemotherapy The efficacy of pemetrexed for injection was evaluated in Study JMEI (NCT00004881), a multicenter, randomized (1:1), open-label study conducted in patients with Stage III or IV NSCLC that had recurred or progressed following one prior chemotherapy regimen for advanced disease

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Multivariate MR analysis and estimation of mediating effects Multivariate MR is an extension of MR that uses genetic variations related to multiple possible exposures to estimate their impact on a single outcome

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