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PanDDA analysis of the 981 processable datasets resulted in 50 hits being identified across different sites of the protein, 28 of which were found in the TIN2 TBM binding site (Fig

Diabetologia 62 , 19881997 (2019)

This age-related decline is not merely inconvenient

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After preliminary functional screening (see below), N-hexanoic-Tyr-Ile-(6)amino-hexanoic amide was chosen for further investigation with the expectation that it would be biologically active, metabolically stable, and BBB permeable