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Inhibiting mTOR signaling in CAR T cells alters immunometabolism and enhances function Intrigued by our pre- and post-infusion results suggesting a significant role for mTOR activity on the efficacy of CAR T cells of LTR, we asked whether we could harness the mTOR pathway to enhance antitumor activity of CAR T cells of STR

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Perspect Pediatr Pathol 1:285311 Chouliaras G, Yiannoutsos CT, Berdoukas V, Ladis V (2009) Cardiac related death in thalassaemia major: time trend and risk factors in a large Greek unit