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No inhibition of the phosphorylation of p38 mitogen-activated protein (MAP) kinase, c-Jun N-terminal kinase (JNK), or extracellular signal-regulated kinase (ERK) was observed as a result of NAC-S2 treatment, suggesting that supersulfides specifically target NF-B signaling [77]

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A further increase by 39.8% in obesity-related DALYs and by 42.7% in obesity-related mortality is expected from 2020 to 2030 1