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Biofilm Maturation: Over time, the microbial community grows and matures, forming a thick, stable biofilm capable of biodegrading a wide range of organic contaminants

5.5 Atypical Fractures Including Femoral Fractures Atypical, low-energy, or low trauma fractures of the femoral shaft have been reported during treatment with bisphosphonates, including zolendronic acid, in patients with osteoporosis

Multiple smaller rashes may develop as the bacteria spread

Everything else comes from animal models

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